---
title: MediPines AGM100 Clinical Applications
description: Clinicians use AGM100 measurements to immediately identify respiratory impairment at the point of care and improve treatment.
---

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# Real-time Cardiorespiratory Status to Improve Patient Care

### AGM100 in Practice

The AGM100 is designed to assess the cardiorespiratory status of patients, including the identification of hypoxia, its severity, and source. It is particularly useful for conditions that affect pulmonary gas exchange, such as COPD, pneumonia, pulmonary embolism, or heart failure, where the transfer of oxygen from the lungs to the blood is immediately detectable.

The measurement of [Oxygen Deficit](https://medipines.com/oxygen-deficit?hsLang=en), provided by the AGM100, indicates the severity of impairment and offers a more comprehensive and precise view of cardiorespiratory status by including the oxygen levels of both the lungs (PAO2) and blood (PaO2), rather than relying solely on blood oxygenation levels.

### Understanding Oxygen Deficit

The measurement of MediPines Oxygen Deficit, provided by the AGM100, is the most informative and comprehensive assessment of gas exchange.

![oxygendeficit-web](https://medipines.com/hs-fs/hubfs/oxygendeficit-web.png?width=301&height=216&name=oxygendeficit-web.png)

## Advance Cardiorespiratory Medicine Throughout the Continuum of Care

- ![Surgery team working together in a surgical room](https://medipines.com/hs-fs/hubfs/Surgery%20team%20working%20together%20in%20a%20surgical%20room.jpeg?width=1000&height=667&name=Surgery%20team%20working%20together%20in%20a%20surgical%20room.jpeg)
- ![Doctor handshaking with a couple at the hospital](https://medipines.com/hs-fs/hubfs/Doctor%20handshaking%20with%20a%20couple%20at%20the%20hospital.jpeg?width=1000&height=667&name=Doctor%20handshaking%20with%20a%20couple%20at%20the%20hospital.jpeg)
- ![Calm doctor touching a medical interface in the hospital](https://medipines.com/hs-fs/hubfs/Calm%20doctor%20touching%20a%20medical%20interface%20in%20the%20hospital.jpeg?width=1000&height=667&name=Calm%20doctor%20touching%20a%20medical%20interface%20in%20the%20hospital.jpeg)
- ![Elderly patient looking at a nurse in hospital ward](https://medipines.com/hs-fs/hubfs/Elderly%20patient%20looking%20at%20a%20nurse%20in%20hospital%20ward.jpeg?width=1000&height=667&name=Elderly%20patient%20looking%20at%20a%20nurse%20in%20hospital%20ward.jpeg)
- ![Doctors using computer whiles theirs colleagues looking at Xray in medical office](https://medipines.com/hs-fs/hubfs/Doctors%20using%20computer%20whiles%20theirs%20colleagues%20looking%20at%20Xray%20in%20medical%20office.jpeg?width=1000&height=667&name=Doctors%20using%20computer%20whiles%20theirs%20colleagues%20looking%20at%20Xray%20in%20medical%20office.jpeg)

### Understanding Oxygen Deficit

The measurement of MediPines Oxygen Deficit, provided by the AGM100, is the most informative and comprehensive assessment of gas exchange.  

[Learn More](https://medipines.com/clinical-research?hsLang=en)

![oxygendefs](https://medipines.com/hs-fs/hubfs/oxygendefs.webp?width=600&height=436&name=oxygendefs.webp)

## Provide patient-centered assessment and care

**Fast, non-invasive assessment of a patient's cardiorespiratory status.**

![agm image (2)](https://medipines.com/hs-fs/hubfs/agm%20image%20(2).png?width=670&height=677&name=agm%20image%20(2).png)

### Cardiorespiratory Assessment

- Immediate results from a simple breathing sample​
- Simultaneously view oxygenation, ventilation, and gas exchange efficiency​
- Use Oxygen Deficit as a marker to determine respiratory impairment severity

### Improve Patient Care

- Quickly rule in or rule out conditions
- Monitor ventilation and perfusion inequality, also known as V/Q mismatch
- Leverage highly reproducible patient measurements 

### Improve Operational Efficiency

- Early identification of decompensating patients
- Accurate medical decision making for escalated care  
- Reliable patient disposition decisions

### Differential Diagnosis and Condition Severity

- Narrow differential diagnosis 
- Monitor patients for respiratory compromise 
- Identify the cause of vague complaints like shortness of breath or chest pain 

### Reduce Post-Operative Risk

- Risk stratify surgical patients 
- Help early identification of atelectasis leading to hypoxemia
- Support identification of post-anesthesia hypoventilation

### Improve Patient Safety

- Avoid harm to patients using non-invasive method
- Reduce unnecessary diagnostic tests or procedures  
- Minimize wait times for lab results, treat patients faster   

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### Latest Articles and Updates

[Medicare Opens New Reimbursement Pathway for MediPines AGM100 Cardiorespiratory Innovation](https://medipines.com/respiratory-medicine-updates/medicare-opens-new-reimbursement-pathway-for-medipines-agm100-cardiorespiratory-innovation?hsLang=en)

ORANGE COUNTY, Calif., Aug. 6, 2025 /PRNewswire/ -- MediPines (www.medipines.com), developer of the award-winning non-invasive cardiorespiratory innovation AGM100®, announced that ...

[Read More](https://medipines.com/respiratory-medicine-updates/medicare-opens-new-reimbursement-pathway-for-medipines-agm100-cardiorespiratory-innovation?hsLang=en)

[MediPines Sponsors 8th Annual CPGLO Summit, hosted by UC San Diego](https://medipines.com/respiratory-medicine-updates/medipines-sponsors-8th-annual-cpglo-summit-hosted-by-uc-san-diego?hsLang=en)

Medipines (https://www.medipines.com) the pioneer in non-invasive cardiorespiratory assessment technology and maker of the AGM100, is proud to sponsor the 8th Annual Center for ...

[Read More](https://medipines.com/respiratory-medicine-updates/medipines-sponsors-8th-annual-cpglo-summit-hosted-by-uc-san-diego?hsLang=en)

[MediPines Announces New Reimbursement Code for Non-Invasive Assessment of Cardiorespiratory Status by the AGM100](https://medipines.com/respiratory-medicine-updates/medipines-announces-reimbursement-code-for-non-invasive-assessment-of-cardiorespiratory-status-by-the-agm100?hsLang=en)

New AMA CPT® Code Establishes Pathway For Clinicians To Submit Claims For Use Of MediPines AGM100®

[Read More](https://medipines.com/respiratory-medicine-updates/medipines-announces-reimbursement-code-for-non-invasive-assessment-of-cardiorespiratory-status-by-the-agm100?hsLang=en)

[MediPines Wins Prestigious Pediatric Medical Device Competition Focused on COVID-19-Related Technologies](https://medipines.com/respiratory-medicine-updates/medipines-wins-prestigious-pediatric-medical-device-competition-focused-on-covid-19-related-technologies?hsLang=en)

MediPines, a respiratory medical device company, was selected a winner in the special COVID-19 edition of the "Make Your Medical Device Pitch for Kids!" competition presented by ...

[Read More](https://medipines.com/respiratory-medicine-updates/medipines-wins-prestigious-pediatric-medical-device-competition-focused-on-covid-19-related-technologies?hsLang=en)

[UCSD Distinguished Lecture Series](https://medipines.com/respiratory-medicine-updates/ucsd-distinguished-lecture-series?hsLang=en)

UCSD John B. West Distinguished Lecture Series, Sponsored by MediPines, to Feature Nobel Laureate Dr. Gregg L. Semenza August 02, 2023 11:57 AM Eastern Daylight Time MediPines, ...

[Read More](https://medipines.com/respiratory-medicine-updates/ucsd-distinguished-lecture-series?hsLang=en)

[Medscape Interview Highlights MediPines AGM100’s 99% Accuracy for Emergency Room Oxygen Therapy Decisions in COVID-19 Patients](https://medipines.com/respiratory-medicine-updates/2022/09/07/medscape-interview-highlights-medipines-agm100s-99-accuracy-for-emergency-room-oxygen-therapy-decisions-in-covid-19-patients?hsLang=en)

YORBA LINDA, Calif.–(BUSINESS WIRE)–In a video interview on “Hot Topics in Emergency Medicine” posted by Medscape, a group of emergency medicine experts and respiratory physiology ...

[Read More](https://medipines.com/respiratory-medicine-updates/2022/09/07/medscape-interview-highlights-medipines-agm100s-99-accuracy-for-emergency-room-oxygen-therapy-decisions-in-covid-19-patients?hsLang=en)

[Medipines Featured in Los Angeles Business Journal](https://medipines.com/respiratory-medicine-updates/2022/09/07/los-angeles-business-journal?hsLang=en)

Innovative Technology Detects Respiratory Impairment Respiratory impairment detection has long been a diagnostic “blind spot,” with the traditional tools available causing ...

[Read More](https://medipines.com/respiratory-medicine-updates/2022/09/07/los-angeles-business-journal?hsLang=en)

[Emergency Department Study Demonstrates Utility of MediPines AGM100 in Triaging COVID-19 Patients](https://medipines.com/respiratory-medicine-updates/2022/06/20/emergency-department-study-demonstrates-utility-of-medipines-agm100-in-triaging-covid-19-patients?hsLang=en)

YORBA LINDA, Calif.–(BUSINESS WIRE)–In a study presented at the American Thoracic Society (ATS) International Conference 2022, the MediPines AGM100 was shown to provide data that ...

[Read More](https://medipines.com/respiratory-medicine-updates/2022/06/20/emergency-department-study-demonstrates-utility-of-medipines-agm100-in-triaging-covid-19-patients?hsLang=en)

[Physicians Use MediPines Non-Invasive Gas-Exchange Analyzer Technology to Assist with Differential Diagnosis for Pulmonary Embolism](https://medipines.com/respiratory-medicine-updates/2022/06/02/physicians-use-medipines-non-invasive-gas-exchange-analyzer-technology-to-assist-with-differential-diagnosis-for-pulmonary-embolism?hsLang=en)

YORBA LINDA, Calif., May 24, 2022–(BUSINESS WIRE)–An increasing number of physicians have been utilizing a unique gas exchange analyzer technology to enhance recognition and ...

[Read More](https://medipines.com/respiratory-medicine-updates/2022/06/02/physicians-use-medipines-non-invasive-gas-exchange-analyzer-technology-to-assist-with-differential-diagnosis-for-pulmonary-embolism?hsLang=en)

## Pulmonary Outpatient Clinics

#### Enhanced cardiorespiratory clinical information

Blood oxygenation, ventilation, and gas exchange simultaneously

Determine cardiorespiratory severity using O2 Deficit (non-invasive A-a gradient)

Establish clear baseline patient measurement prior to procedure

#### Increased operational efficiency

2-minute test allows MA to collect data and update chart before being seen by the MD

Automatic steady state recognition for repeatable result to test treatment effectiveness

Immediate results in office for faster clinical decisions

#### Assess patients in the clinic

Fully reimbursable procedure

Reduce the number of patients sent to lab or ER for similar information

Objective, repeatable test improves monitoring patients over time

 

## Hospitals - Step Down, Critical Care, ER

#### Care path decisions and operational efficiency

Use O2 Deficit to make home/observe/admission decisions

Use O2 Deficit to predict the need for escalated care like supplemental oxygen

Identify hypoxic condition and sources of hypoxemia to direct treatment

#### Differential diagnosis and condition severity

Use O2 Deficit for differential diagnosis e.g., NSTEMI vs PE

Determine cardiorespiratory severity using O2 Deficit (non-invasive A-a gradient)

Add clarity in diffuse chief complaints like shortness of breath or chest pain

#### Relevant to Cardiology, Pulmonology, Respiratory

Used with quick response team to help identify the chief problem

Use O2 Deficit as a surrogate for V/Q matching

Objective, repeatable test improves monitoring patients over time

 

## Surgical Procedures

#### Preoperative Gas Exchange Assessment

Risk stratify surgical patients for postoperative pulmonary complications

Preoperative evaluation to determine oxygenation strategies

Establish baseline measurement prior to anesthesia

 

#### Postoperative Gas Exchange Assessment

Monitor for residual shunt from the intra-operative period

Early identification of atelectasis leading to hypoxemia

Monitor for post-anesthesia hypoventilation

 

#### Improved Patient Discharge Safety

Confirm gas exchange efficiency before patient discharge

Reduce avoidable postoperative pulmonary complications

Confirm pharmacological effectiveness

 

## Interventional Procedures

#### Before diagnostic cardiac catheterizations and imaging

Identify hypoxic condition and sources of hypoxemia to direct treatment

Complement ultrasound to determine severity using O2 Deficit (non-invasive A-a gradient)

Establish clear baseline patient measurement prior to procedure

#### During procedures aimed at improving V/Q matching

Confirm degree of the blockage being treated

Identify secondary blockages with changes in gas exchange

Maintain stable V/Q matching before ending the procedure

 

#### Post procedures and patient follow up

Confirm pharmacological effectiveness before patient discharge

Use oxygen deficit to approximate pulmonary vascular pressures

Manage fluid buildup (edema) in heart failure to avoid readmission

 

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